What does equivocal Lyme test mean?
(3) There is an “equivocal” category for both IgG and IgM blots which indicates that although there are not sufficient antibody bands present for the blot to be reactive, there is significant immunologic activity that may be related to Lyme disease. Result.
What is the most accurate test for Lyme disease?
A blood test does not only detect Lyme disease; it is the most accurate and preferred test for diagnosing the disease. If a patient with Lyme disease shows signs that the central nervous system has been affected by the disease, western blot testing on the cerebrospinal fluid (CSF) can be performed.
Is band 41 Lyme specific?
What is the significance of band 41 on the IgM and IgG Western blot? It is not Lyme specific and the CDC requires more bands to be present before a diagnosis. However, it is a band for bacteria so what else could cause that to be positive if not Lyme? The 41 kd band is often found on the Western blot.
What does a positive IgG Lyme test mean?
Most of the time, the IgG western blot must be positive in order to indicate a potential infection with Lyme disease. The IgM antibodies are the first antibodies to be produced in the body in response to an infection.
What are equivocal results?
“Equivocal” means results cannot be interpreted as positive or negative because they are below the limit of detection (see below). Reasons may be: Very early or late in infection.
Can you have Lyme disease with a negative Western blot?
If you have been infected for longer than 4 to 6 weeks and the IgG Western Blot is still negative, it is highly likely that the IgM result is incorrect (e.g., a false positive). This does not mean that you are not ill, but it does suggest that the cause of illness is something other than the Lyme disease bacterium.
What does it mean if 41 kd IgG band is reactive?
What does it mean if your 41 KD (IGG) Band result is too high? Two types of antibodies are detected in the Western blot test. This particular marker is called 41 KD (IGG) Band and hence is a IgG antibody marker. IgG antibodies are a sign of an older infection.
How long does Lyme IgG stay positive?
IgG antibodies are slower to develop, beginning to show 4-6 weeks after exposure and may peak 4-6 months after exposure. While IgM tends to be associated with an active infection, both IgM and IgG can persist in the blood for many years.
Can Borrelia burgdorferi be cultured?
burgdorferi in patient samples, (ii) the reference strain of B. burgdorferi will not grow in MPM medium, (iii) BSK-H medium remains the best medium for cultivation of B. burgdorferi, and (iv) blood culture of patients suspected to have Lyme disease is a low-yield test.
What is Lyme 41 kd IgG?