Is acetyl chloride hazardous?

can severely irritate and burn the skin and eyes. exposures may cause a build-up of fluid in the lungs (pulmonary edema), a medical emergency. DANGEROUS FIRE and EXPLOSION HAZARD. No occupational exposure limits have been established for Acetyl Chloride.

What are the uses of acetyl chloride?

Acetyl chloride is used in organic synthesis as an acetylating agent and in testing for water and/ or cholesterol in organic liquids, in the pharmaceutical industry and in pesticide manufacture.

How do you make acetyl chloride?

When heated, a mixture of dichloroacetyl chloride and acetic acid gives acetyl chloride. It can also be synthesized from the catalytic carbonylation of methyl chloride. It also arises from the reaction of acetic acid, acetonitrile, and hydrogen chloride.

What is RCOCl?

In organic chemistry, an acyl chloride (or acid chloride) is an organic compound with the functional group -COCl. Their formula is usually written RCOCl, where R is a side chain. They are reactive derivatives of carboxylic acids.

How do you handle acetyl chloride?

DO NOT USE WATER. Keep Acetyl Chloride out of confined spaces, such as sewers, because of the possibility of an explosion. DO NOT wash into sewer. Hazardous to the environment, especially to water.

Why does acetyl chloride react with water?

Adding an acyl chloride to water produces the corresponding carboxylic acid together with steamy acidic fumes of hydrogen chloride. The reaction is usually extremely vigorous at room temperature.

What is the purpose of acetylation?

Acetylation is a modification that can dramatically change the function of a protein through alteration of its properties, including hydrophobicity, solubility, and surface properties, all of which may influence protein conformation and interactions with substrates, cofactors and other macromolecules.

Is acetyl chloride an acid or base?

Acetyl chloride, also known as ethanoyl chloride, is an acid chloride (also known as an acyl chloride) derived from acetic acid (ethanoic acid). It has the formula CH3COCl and it belongs to the class of organic compounds called acyl halides.

How do you distill acetyl chloride?

Preparation of Acetyl Chloride The distillation flask is heated to about 45°C by placing it on a water heater. By doing this, all the hydrogen chloride gas formed in the reaction is removed. After that heat the flask to about 55°C. At this temperature, acetyl chloride is distilled and collected in the receptor.

What does acyl stand for?

acyl. [ ăs′əl ] n. A organic radical having the general formula RCO, derived from the removal of a hydroxyl group from an organic acid.

What is Rcoo?

In organic chemistry, a carboxylate is the conjugate base of a carboxylic acid, RCOO − (or RCO−2). It is an ion with negative charge.

Is acetyl chloride soluble in water?

Acetyl chloride is an organic compound, an acyl chloride derived from acetic acid. It has the formula CH3COCl….Acetyl chloride.

Density 1.104 g/cm3
Melting point −112 °C (−170 °F; 161 K)
Boiling point 52 °C (126 °F; 325 K)
Solubility in water Reacts

What are the MSDS catalog numbers for acetyl chloride?

MSDS Name:Acetyl chloride Catalog Numbers:AC151270000, AC151270010, AC151270025, AC151275000, AC219470000, AC219470250, AC219472500, A27-250 Synonyms:Acetic acid chloride; Ethanoyl chloride. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call:201-796-7100 Emergency Number:201-796-7100

What is the formula for acetyl chloride?

Acetyl chloride is an acyl chloride. It derives from an acetic acid. acetyl chloride Computed by LexiChem 2.6.6 (PubChem release 2019.06.18) InChI=1S/C2H3ClO/c1-2 (3)4/h1H3 Computed by InChI 1.0.5 (PubChem release 2019.06.18) WETWJCDKMRHUPV-UHFFFAOYSA-N Computed by InChI 1.0.5 (PubChem release 2019.06.18) CC (=O)Cl

What is acetyl chloride used for?

Acetyl chloride is a powerful acetylating agent. It is used in the manufacture of aspirin, acetaminophen, acetanilide, and acetophenone. Liquid crystal compositions for optical display and memory devices frequently require acetyl chloride.

Is acetyl chloride on the health&safety reporting list?

ACETYL CHLORIDE Hazard Class: 3 3(8) UN Number: UN1717 UN1717 Packing Group: II II Additional Info: FLASHPOINT 4C Section 15 – Regulatory Information US FEDERAL TSCA CAS# 75-36-5 is listed on the TSCA inventory. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules