What does Hypocellular mean?
Hypocellular is a term pathologists use to describe a decreased number of cells compared to normal in that area of the body. It is a descriptive term and not a diagnosis. Hypocellular can be used to describe both benign (non-cancerous) groups of cells and malignant (cancerous) tumours.
What does it mean when bone marrow is Hypocellular?
Hypocellular AML is currently defined as AML with a bone marrow cellularity less than 20%, although in some earlier reports, cellularity less than 40% or 50% was considered to be hypocellular.
What causes Hypocellularity?
Abstract. Pancytopenia with hypocellular bone marrow most often is caused by idiopathic aplastic anemia, but can be caused by inherited bone marrow failure syndromes, drugs, infections, nutritional deficiencies, and rheumatologic disease.
What does Hypocellular specimen mean?
Abstract. Bladder wash flow cytometry specimens containing less than 1,000 cells were defined as hypocellular.
What is Hypercellular bone marrow?
Hypercellular marrow can occur when there is increased production in one or more cell lineages or there is an increased number of neoplastic cells (acute leukemia, multiple myeloma, histiocytic sarcoma, etc.).
How is Hypocellular bone marrow treated?
Young patients with Hypocellular marrow (SAA, VSAA, MDS) ideally need ALLO SCT or Triple Immunosupression with ATG + Cyclosporin + Steroids therapy. However these therapies are very expensive and affordable to very few in third world poor countries.
What is Hypercellular?
Medical Definition of hypercellularity : the presence of an abnormal excess of cells (as in bone marrow)
Can bone marrow disease be cured?
A bone marrow transplant is the only cure for aplastic anemia. Bone marrow transplants are also called stem cell transplants. A transplant is the preferred treatment for severe aplastic anemia. Bone marrow transplants replace damaged stem cells with healthy ones.
How long can you live with bone marrow failure?
Bone marrow failure: The incidence of bone marrow failure is 50% at 50 years of age. The majority of deaths (67%) are a result of bone marrow failure, followed by cancer and lung disease (pulmonary fibrosis) with or without HSCT. Overall median survival has improved to 49 years from 34 years in the past decade.
What does Hypercellularity mean?
Hypercellular is a term pathologists use to describe an increased number of cells compared to normal in an area of the body. It is a descriptive term and not a diagnosis. Hypercellular can be used to describe both benign (non-cancerous) groups of cells and malignant (cancerous) tumours.
What is hematopoietic cell?
(hee-MA-toh-poy-EH-tik stem sel) An immature cell that can develop into all types of blood cells, including white blood cells, red blood cells, and platelets. Hematopoietic stem cells are found in the peripheral blood and the bone marrow. Also called blood stem cell.
What is Hypocellular myelodysplastic syndrome?
Hypocellular MDS was defined as bone marrow cellularity less than 30% in patients younger than 70 years, or less than 20% in patients older than 70 years. Clinical characteristics and treatment outcomes between hypocellular MDS and normo/hypercellular MDS were compared.