What is the drug KAYEXALATE used for?
This medication is used to treat a high level of potassium in your blood. Too much potassium in your blood can sometimes cause heart rhythm problems. Sodium polystyrene sulfonate works by helping your body get rid of extra potassium.
How does KAYEXALATE lower potassium?
KAYEXALATE increases fecal potassium excretion through binding of potassium in the lumen of the gastrointestinal tract. Binding of potassium reduces the concentration of free potassium in the gastrointestinal lumen, resulting in a reduction of serum potassium levels.
What are the side effects of KAYEXALATE?
Common side effects of Kayexalate include:
- loss of appetite,
- upset stomach,
- constipation, or.
Does KAYEXALATE induce diarrhea?
KAYEXALATE may cause some degree of gastric irritation. Anorexia, nausea, vomiting, and constipation may occur especially if high doses are given. Also, hypokalemia, hypocalcemia, and significant sodium retention, and their related clinical manifestations, may occur (see WARNINGS). Occasionally diarrhea develops.
Why is Kayexalate used in renal patients?
Kayexalate® (sodium polystyrene sulfonate) is a medication that treats high potassium levels in the body. If not treated, high potassium levels may lead to an irregular heartbeat or cause problems with muscles and nerves. Why do hemodialysis patients need this medication?
How do you take Kayexalate?
KAYEXALATE powder is usually given by mouth mixed in a small amount of water. It can also be mixed with food or sweetened liquid Do NOT mix KEYEXALATE with orange juice or fruit juice which contains potassium. KAYEXALATE is a powder. Be careful not to inhale it accidentally.
When should Kayexalate be given?
ORAL DOSING When taken by mouth, KAYEXALATE should be taken at least 3 hours before or 3 hours after other oral medications. For patients with gastroparesis (a condition preventing your stomach from emptying properly), a 6-hour separation should be considered.
Why was Kayexalate discontinued?
However, the U.S. Food and Drug Administration (FDA) has issued a warning to avoid Kayexalate administration with sorbitol due to the risk of colonic necrosis associated with sorbitol administration.
Should Kayexalate be taken with food?
ORAL DOSING KAYEXALATE powder is usually given by mouth mixed in a small amount of water. It can also be mixed with food or sweetened liquid Do NOT mix KEYEXALATE with orange juice or fruit juice which contains potassium.
Can dialysis patients take Kayexalate?
How do I take Kayexalate®? hemodialysis staff tells you to, even if you miss a dialysis treatment. Take it at least 3 hours before or 3 hours after any other oral (taken by mouth) medications. Take this medication for as long as the hemodialysis staff tells you to.
How much does 15g Kayexalate lower potassium?
This drug has been a standard part of treatment of hyperkalemia for decades. Many of us were taught that if you give a patient a dose of kayexalate, you should expect there serum potassium to drop by 0.5 – 1.0 mEq in 4-6 hours.
When should KAYEXALATE be given?
Is Kayexalate safe for children?
Kayexalate belongs to a class of drugs called Potassium Binders. It is not known if Kayexalate is safe and effective in children. What are the possible side effects of Kayexalate? Kayexalate may cause serious side effects including:
What is Kayexalate?
Kayexalate Generic name: sodium polystyrene sulfonate Dosage form: powder, for suspension Drug class: Cation exchange resins
Can Kayexalate cause intestinal necrosis?
Intestinal Necrosis. Cases of intestinal necrosis, some fatal, and other serious gastrointestinal adverse events (bleeding, ischemic colitis, perforation) have been reported in association with KAYEXALATE use. The majority of these cases reported the concomitant use of sorbitol.