Why is cake formed in suspension?
In a deflocculated suspension, the individual particles remain as discrete separated units and settle slowly. The slow rate of settling of particles prevents the individual particles of this suspension to entrap any liquid medium and becomes compacted leading to cake formation.
In which suspension cake is formed?
Differences between flocculated and deflocculated suspensions
| Flocculated suspensions | |
|---|---|
| 3. | Sediment formed is loosely packed and does not form a hard cake. |
| 4. | Sediment can be easily redispersed on shaking. |
| 5. | Lack of elegance since the particles of the dispersed phase tend to separate from the dispersion medium |
What are the 2 types of suspension in pharmacy?
2. Classification of suspension based on the concentration of the dispersed phase. Based on the concentration of the dispersed phase, suspensions can be classified as dilute and concentrated suspension.
What are the flocculated and Deflocculated suspension?
Definition. Flocculated Suspension: A flocculated suspension is a suspension in which particles have undergone flocculation. Deflocculated Suspension: A deflocculated suspension is a suspension where no flocculation has taken place.
What are the qualities of good suspension?
1 It should settle slowly and should be readily re-dispersed on gentle shaking of the container. 2 The particle size of the suspension remains fairly constant throughout its long period of undisturbed standing . 3 The suspension should pour readily and evenly from its container.
Why are medicines prepared as suspensions?
Substances can be chemically unstable, insoluble in water, distasteful etc. Suspensions are often used as a dosage form when the drug is insoluble in water and when use of solubilizing agents is not possible.
What is difference between emulsion and suspension?
Mixtures can be of many types like a solution, suspension and colloids. A mixture can be classified into two types, homogeneous mixture and heterogeneous mixture….Difference between Suspension and Emulsion.
| Suspension | Emulsion |
|---|---|
| Solid particles are dispersed in any medium, that can be solid, gas or liquid | Both dispersed phase and the dispersion medium are liquid |
What is a drug suspension?
A suspension is a liquid with small pieces of drug. The drug is not complete dissolved in the solution. Whenever you take a suspension, you should always shake (or stir) it so that you receive the right amount of drug every time you take it.
What is caking flocculation suspension?
Relatively strong bonding forces develop between the suspended particles, and floccules are formed. Caking of the sulfamerazine suspension system is seen when the particles settle to a dense sediment before bonds can be established between the closely-packed particles.
What does flocculated suspension mean?
Definition. Flocculation is a process whereby small particles in suspension are caused to aggregate, giving large clusters (flocs) that are much more easily separated than the original particles. The process is in widespread use in many industrial applications.
What is stability of suspension?
It is important to understand that suspensions are kinetically stable, but thermodynamically unstable, system. Physical stability is defined as the condition in which the particles remain uniformly distributed throughout the dispersion without any signs of sedimentation.
What is meant by the term “caking”?
Caking is a consequence of chemical reactions of grain surfaces. Often these reactions involve adsorption of water vapor or other gases. Crystalline solids often cake by formation of liquid bridge between microcrystals and subsequent fusion of a solid bridge. Amorphous materials can cake by glass transitions and changes in viscosity.
What do you mean by suspension?
Definition of suspension. (3) : a system consisting of a solid dispersed in a solid, liquid, or gas usually in particles of larger than colloidal size — compare emulsion.
What is the mechanism of caking?
Caking mechanisms depend on the nature of the material. Caking is a consequence of chemical reactions of grain surfaces. Often these reactions involve adsorption of water vapor or other gases.
Why do particles of suspended materials not form a cake?
Particles do not bond tightly to each other and a hard, dense cake does not form. The sediment is easy to redisperse, so as to reform the original suspension. The suspension has a pleasing appearance, since the suspended material remains suspended for a relatively long time.